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Mitochondrial folate pathway regulates myofibroblast differentiation and silica-induced pulmonary fibrosis

BACKGROUND: Silica-induced pulmonary fibrosis (silicosis) is a diffuse interstitial fibrotic disease characterized by the massive deposition of extracellular matrix in lung tissue. Fibroblast to myofibroblast differentiation is crucial for the disease progression. Inhibiting myofibroblast differenti...

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Detalles Bibliográficos
Autores principales: Qu, Yaqian, Zhai, Ruonan, Wang, Dandan, Wang, Zheng, Hou, Guangjie, Wu, Chenchen, Tang, Meian, Xiao, Xiongbin, Jiao, Jie, Ba, Yue, Zhou, Fang, Qiu, Jian, Yao, Wu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10245413/
https://www.ncbi.nlm.nih.gov/pubmed/37280614
http://dx.doi.org/10.1186/s12967-023-04241-0