Cargando…

Mitochondrial folate pathway regulates myofibroblast differentiation and silica-induced pulmonary fibrosis

BACKGROUND: Silica-induced pulmonary fibrosis (silicosis) is a diffuse interstitial fibrotic disease characterized by the massive deposition of extracellular matrix in lung tissue. Fibroblast to myofibroblast differentiation is crucial for the disease progression. Inhibiting myofibroblast differenti...

Descripción completa

Detalles Bibliográficos
Autores principales:	Qu, Yaqian, Zhai, Ruonan, Wang, Dandan, Wang, Zheng, Hou, Guangjie, Wu, Chenchen, Tang, Meian, Xiao, Xiongbin, Jiao, Jie, Ba, Yue, Zhou, Fang, Qiu, Jian, Yao, Wu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10245413/ https://www.ncbi.nlm.nih.gov/pubmed/37280614 http://dx.doi.org/10.1186/s12967-023-04241-0

Ejemplares similares

MiR‐503 suppresses fibroblast activation and myofibroblast differentiation by targeting VEGFA and FGFR1 in silica‐induced pulmonary fibrosis
por: Wu, Qiuyun, et al.
Publicado: (2020)

miR-let-7d attenuates EMT by targeting HMGA2 in silica-induced pulmonary fibrosis
por: Yu, Xinghao, et al.
Publicado: (2019)

Investigation of folate-conjugated fluorescent silica nanoparticles for targeting delivery to folate receptor-positive tumors and their internalization mechanism
por: Yang, Hong, et al.
Publicado: (2011)

Mitochondrial folate metabolism–mediated α-linolenic acid exhaustion masks liver fibrosis resolution
por: Gao, Yanjie, et al.
Publicado: (2023)

Tetrandrine slows the radiographic progression of progressive massive fibrosis in pneumoconiosis: a retrospective cohort study
por: Tang, Meian, et al.
Publicado: (2023)

Origin of myofibroblasts in liver fibrosis
por: Brenner, David A, et al.
Publicado: (2012)

COVID-19 Infection May Drive EC-like Myofibroblasts towards Myofibroblasts to Contribute to Pulmonary Fibrosis
por: Wu, Xiuju, et al.
Publicado: (2023)

Astaxanthin prevents pulmonary fibrosis by promoting myofibroblast apoptosis dependent on Drp1-mediated mitochondrial fission
por: Zhang, Jinjin, et al.
Publicado: (2015)

Lung Fibrosis and Fibrosis in the Lungs: Is It All about Myofibroblasts?
por: Ortiz-Zapater, Elena, et al.
Publicado: (2022)

Genome-wide DNA methylation analysis of Astragalus and Danshen on the intervention of myofibroblast activation in idiopathic pulmonary fibrosis
por: Liu, Qingyin, et al.
Publicado: (2023)

Folate receptor targeting silica nanoparticle probe for two-photon fluorescence bioimaging
por: Wang, Xuhua, et al.
Publicado: (2010)

Inactivation of myofibroblasts during regression of liver fibrosis
por: Kisseleva, Tatiana, et al.
Publicado: (2013)

Decoding myofibroblast origins in human kidney fibrosis
por: Kuppe, Christoph, et al.
Publicado: (2021)

The role of the macrophage-to-myofibroblast transition in renal fibrosis
por: Wei, Jia, et al.
Publicado: (2022)

p53 and Myofibroblast Apoptosis in Organ Fibrosis
por: McElhinney, Kealan, et al.
Publicado: (2023)

Noncoding RNAs: Master Regulator of Fibroblast to Myofibroblast Transition in Fibrosis
por: Zhang, Huamin, et al.
Publicado: (2023)

Blocking Mitochondrial Pyruvate Transport Alters Corneal Myofibroblast Phenotype: A New Target for Treating Fibrosis
por: Jeon, Kye-Im, et al.
Publicado: (2023)

Genetic lineage tracing reveals stellate cells as contributors to myofibroblasts in pancreas and islet fibrosis
por: Wang, Jinbang, et al.
Publicado: (2023)

Disruption of myofibroblastic Notch signaling attenuates liver fibrosis by modulating fibrosis progression and regression
por: Yue, Zhensheng, et al.
Publicado: (2021)

The types of hepatic myofibroblasts contributing to liver fibrosis of different etiologies
por: Xu, Jun, et al.
Publicado: (2014)

Novel Mechanism of the Pericyte-Myofibroblast Transition in Renal Interstitial Fibrosis: Core Fucosylation Regulation
por: Wang, Nan, et al.
Publicado: (2017)

Inflammatory macrophages can transdifferentiate into myofibroblasts during renal fibrosis
por: Meng, Xiao-Ming, et al.
Publicado: (2016)

Regulating the cell shift of endothelial cell-like myofibroblasts in pulmonary fibrosis
por: Wu, Xiuju, et al.
Publicado: (2023)

Epithelial and interstitial Notch1 activity contributes to the myofibroblastic phenotype and fibrosis
por: Hong, Weilong, et al.
Publicado: (2019)

The myofibroblast in wound healing and fibrosis: answered and unanswered questions
por: Bochaton-Piallat, Marie-Luce, et al.
Publicado: (2016)

Experimental systems to study the origin of the myofibroblast in peritoneal fibrosis
por: Padwal, Manreet, et al.
Publicado: (2016)

Myofibroblasts and lung fibrosis induced by carbon nanotube exposure
por: Dong, Jie, et al.
Publicado: (2016)

Stromal and immune cells in gut fibrosis: the myofibroblast and the scarface
por: Valatas, Vassilis, et al.
Publicado: (2017)

PD-1/PD-L1 axis in organ fibrosis
por: Zhao, Youliang, et al.
Publicado: (2023)

Synthesis and characterization of folate-functionalized silica-based materials and application for bioimaging of cancer cells
por: Zare, Yalda, et al.
Publicado: (2023)

Mitochondrial uncoupling protein‐2 reprograms metabolism to induce oxidative stress and myofibroblast senescence in age‐associated lung fibrosis
por: Rangarajan, Sunad, et al.
Publicado: (2022)

Defining the Role of Mitochondrial Fission in Corneal Myofibroblast Differentiation
por: Jeon, Kye-Im, et al.
Publicado: (2022)

Nitric oxide modulates folate-mediated one-carbon metabolism and mitochondrial energy levels of peaches during cold storage
por: Yang, Zhifeng, et al.
Publicado: (2023)

Mechanisms of pulmonary fibrosis: role of activated myofibroblasts and NADPH oxidase
por: Thannickal, Victor J
Publicado: (2012)

Fibrosis: recent advances in myofibroblast biology and new therapeutic perspectives
por: Hinz, Boris, et al.
Publicado: (2010)

CXC-Type Chemokines Promote Myofibroblast Phenoconversion and Prostatic Fibrosis
por: Gharaee-Kermani, Mehrnaz, et al.
Publicado: (2012)

The Role of NADPH Oxidases (NOXs) in Liver Fibrosis and the Activation of Myofibroblasts
por: Liang, Shuang, et al.
Publicado: (2016)

Metformin induces lipogenic differentiation in myofibroblasts to reverse lung fibrosis
por: Kheirollahi, Vahid, et al.
Publicado: (2019)

Myofibroblasts: Function, Formation, and Scope of Molecular Therapies for Skin Fibrosis
por: Tai, Yifan, et al.
Publicado: (2021)

Implant Fibrosis and the Underappreciated Role of Myofibroblasts in the Foreign Body Reaction
por: Noskovicova, Nina, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_in58lmndl7guuprd76s46mm5at