Not every estimate counts – evaluation of cell composition estimation approaches in brain bulk tissue data

BACKGROUND: Variation in cell composition can dramatically impact analyses in bulk tissue samples. A commonly employed approach to mitigate this issue is to adjust statistical models using estimates of cell abundance derived directly from omics data. While an arsenal of estimation methods exists, th...

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Detalles Bibliográficos
Autores principales: Toker, Lilah, Nido, Gonzalo S., Tzoulis, Charalampos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10245417/
https://www.ncbi.nlm.nih.gov/pubmed/37287013
http://dx.doi.org/10.1186/s13073-023-01195-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10245417/
https://www.ncbi.nlm.nih.gov/pubmed/37287013
http://dx.doi.org/10.1186/s13073-023-01195-2

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