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Not every estimate counts – evaluation of cell composition estimation approaches in brain bulk tissue data

BACKGROUND: Variation in cell composition can dramatically impact analyses in bulk tissue samples. A commonly employed approach to mitigate this issue is to adjust statistical models using estimates of cell abundance derived directly from omics data. While an arsenal of estimation methods exists, th...

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Detalles Bibliográficos
Autores principales:	Toker, Lilah, Nido, Gonzalo S., Tzoulis, Charalampos
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10245417/ https://www.ncbi.nlm.nih.gov/pubmed/37287013 http://dx.doi.org/10.1186/s13073-023-01195-2

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