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In vitro fitness of SARS-CoV-2 variants as assessed by competition experiments followed by ddRT-PCR and whole genome sequencing

OBJECTIVE: To develop a new method for reliable and rapid determination of the fitness of SARS-CoV-2 variants of concern. METHODS: Competition experiments between two SARS-CoV-2 variants were performed in cells of the upper (nasal human airway epithelium) and lower (Calu-3 cells) respiratory tracts...

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Detalles Bibliográficos
Autores principales: Hénaut, Mathilde, Carbonneau, Julie, Rhéaume, Chantal, Levade, Ines, Boivin, Guy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10245455/
https://www.ncbi.nlm.nih.gov/pubmed/37321149
http://dx.doi.org/10.1016/j.jcv.2023.105517