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MicroRNA-29a-3p prevents Schistosoma japonicum-induced liver fibrosis by targeting Roundabout homolog 1 in hepatic stellate cells

BACKGROUND: Schistosomiasis is a serious but neglected parasitic disease in humans that may lead to liver fibrosis and death. Activated hepatic stellate cells (HSCs) are the principal effectors that promote the accumulation of extracellular matrix (ECM) proteins during hepatic fibrosis. Aberrant mic...

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Detalles Bibliográficos
Autores principales: Kong, Hongyan, Song, Qiqin, Hu, Wenjiang, Guo, Shusen, Xiang, Dandan, Huang, Shuaiwen, Xu, Xin, He, Jinan, Pan, Lanyue, Tao, Ran, Yu, Haijing, Huang, Jiaquan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10245502/
https://www.ncbi.nlm.nih.gov/pubmed/37280619
http://dx.doi.org/10.1186/s13071-023-05791-4