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Nebulised mesenchymal stem cell derived extracellular vesicles ameliorate E. coli induced pneumonia in a rodent model

BACKGROUND: Mesenchymal stem cell (MSC) derived extracellular vesicles (EVs) have been proposed as an alternative to cell therapy, creating new possible delivery modalities such as nebulisation. We wished to investigate the therapeutic potential of directly nebulised MSC-EVs in the mitigation of Esc...

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Detalles Bibliográficos
Autores principales: Gonzalez, Hector, McCarthy, Sean, Masterson, Claire, Byrnes, Declan, Sallent, Ignacio, Horan, Emma, Elliman, Stephen J., Vella, Gabriele, Prina-Mello, Adriele, Silva, Johnatas D., Krasnodembskaya, Anna D., MacLoughlin, Ronan, Laffey, John G., O’Toole, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10245544/
https://www.ncbi.nlm.nih.gov/pubmed/37280647
http://dx.doi.org/10.1186/s13287-023-03385-6