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Cul3 substrate adaptor SPOP targets Nup153 for degradation

SPOP is a Cul3 substrate adaptor responsible for degradation of many proteins related to cell growth and proliferation. Because mutation or misregulation of SPOP drives cancer progression, understanding the suite of SPOP substrates is important to understanding regulation of cell proliferation. Here...

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Detalles Bibliográficos
Autores principales: Ong, Joseph Y., Torres, Jorge Z.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10245568/
https://www.ncbi.nlm.nih.gov/pubmed/37293018
http://dx.doi.org/10.1101/2023.05.13.540659