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Tumor Cytokine-Induced Hepatic Gluconeogenesis Contributes to Cancer Cachexia: Insights from Full Body Single Nuclei Sequencing

A primary cause of death in cancer patients is cachexia, a wasting syndrome attributed to tumor-induced metabolic dysregulation. Despite the major impact of cachexia on the treatment, quality of life, and survival of cancer patients, relatively little is known about the underlying pathogenic mechani...

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Detalles Bibliográficos
Autores principales: Liu, Ying, Dantas, Ezequiel, Ferrer, Miriam, Liu, Yifang, Comjean, Aram, Davidson, Emma E., Hu, Yanhui, Goncalves, Marcus D., Janowitz, Tobias, Perrimon, Norbert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10245574/
https://www.ncbi.nlm.nih.gov/pubmed/37292804
http://dx.doi.org/10.1101/2023.05.15.540823