P2X7 receptor inhibition ameliorates ubiquitin–proteasome system dysfunction associated with Alzheimer’s disease

BACKGROUND: Over recent years, increasing evidence suggests a causal relationship between neurofibrillary tangles (NFTs) formation, the main histopathological hallmark of tauopathies, including Alzheimer’s disease (AD), and the ubiquitin–proteasome system (UPS) dysfunction detected in these patients...

Descripción completa

Detalles Bibliográficos
Autores principales: Bianchi, Carolina, Alvarez-Castelao, Beatriz, Sebastián-Serrano, Álvaro, Di Lauro, Caterina, Soria-Tobar, Lucia, Nicke, Annette, Engel, Tobias, Díaz-Hernández, Miguel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10245610/
https://www.ncbi.nlm.nih.gov/pubmed/37287063
http://dx.doi.org/10.1186/s13195-023-01258-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10245610/
https://www.ncbi.nlm.nih.gov/pubmed/37287063
http://dx.doi.org/10.1186/s13195-023-01258-x

Ejemplares similares