P2X7 receptor inhibition ameliorates ubiquitin–proteasome system dysfunction associated with Alzheimer’s disease

BACKGROUND: Over recent years, increasing evidence suggests a causal relationship between neurofibrillary tangles (NFTs) formation, the main histopathological hallmark of tauopathies, including Alzheimer’s disease (AD), and the ubiquitin–proteasome system (UPS) dysfunction detected in these patients...

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Detalles Bibliográficos
Autores principales: Bianchi, Carolina, Alvarez-Castelao, Beatriz, Sebastián-Serrano, Álvaro, Di Lauro, Caterina, Soria-Tobar, Lucia, Nicke, Annette, Engel, Tobias, Díaz-Hernández, Miguel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10245610/
https://www.ncbi.nlm.nih.gov/pubmed/37287063
http://dx.doi.org/10.1186/s13195-023-01258-x

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