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Subtype-specific circadian clock dysregulation modulates breast cancer biology, invasiveness, and prognosis

Studies in shift workers and model organisms link circadian disruption to breast cancer. However, molecular rhythms in non-cancerous and cancerous human breast tissues are largely unknown. We reconstructed rhythms informatically, integrating locally collected, time-stamped biopsies with public datas...

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Detalles Bibliográficos
Autores principales: Hammarlund, Jan A, Li, Shi-Yang, Wu, Gang, Lian, Jia-wen, Howell, Sacha J, Clarke, Rob, Adamson, Antony, Gonçalves, Cátia F., Hogenesch, John B, Meng, Qing-Jun, Anafi, Ron C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10245642/
https://www.ncbi.nlm.nih.gov/pubmed/37293090
http://dx.doi.org/10.1101/2023.05.17.540386