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Automated model building and protein identification in cryo-EM maps

Interpreting electron cryo-microscopy (cryo-EM) maps with atomic models requires high levels of expertise and labour-intensive manual intervention. We present ModelAngelo, a machine-learning approach for automated atomic model building in cryo-EM maps. By combining information from the cryo-EM map w...

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Detalles Bibliográficos
Autores principales: Jamali, Kiarash, Käll, Lukas, Zhang, Rui, Brown, Alan, Kimanius, Dari, Scheres, Sjors H.W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10245678/
https://www.ncbi.nlm.nih.gov/pubmed/37292681
http://dx.doi.org/10.1101/2023.05.16.541002