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Centromere-specifying nucleosomes persist in aging mouse oocytes in the absence of nascent assembly
Centromeres direct genetic inheritance but are not themselves genetically encoded. Instead, centromeres are defined epigenetically by the presence of a histone H3 variant, CENP-A(1). In cultured somatic cells, an established paradigm of cell cycle-coupled propagation maintains centromere identity: C...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Cold Spring Harbor Laboratory
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10245701/ https://www.ncbi.nlm.nih.gov/pubmed/37292821 http://dx.doi.org/10.1101/2023.05.18.541332 |