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scTIE: data integration and inference of gene regulation using single-cell temporal multimodal data

Single-cell technologies offer unprecedented opportunities to dissect gene regulatory mechanisms in context-specific ways. Although there are computational methods for extracting gene regulatory relationships from scRNA-seq and scATAC-seq data, the data integration problem, essential for accurate ce...

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Detalles Bibliográficos
Autores principales: Lin, Yingxin, Wu, Tung-Yu, Chen, Xi, Wan, Sheng, Chao, Brian, Xin, Jingxue, Yang, Jean Y.H., Wong, Wing H., Wang, Y. X. Rachel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10245711/
https://www.ncbi.nlm.nih.gov/pubmed/37292801
http://dx.doi.org/10.1101/2023.05.18.541381