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A regulatory role for the unstructured C-terminal domain of the CtBP transcriptional corepressor

The C-terminal Binding Protein (CtBP) is a transcriptional corepressor that plays critical roles in development, tumorigenesis, and cell fate. CtBP proteins are structurally similar to alpha hydroxyacid dehydrogenases and feature a prominent intrinsically disordered region in the C-terminus. In the...

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Detalles Bibliográficos
Autores principales: Raicu, Ana-Maria, Suresh, Megha, Arnosti, David N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10245716/
https://www.ncbi.nlm.nih.gov/pubmed/37292674
http://dx.doi.org/10.1101/2023.05.19.541472