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A regulatory role for the unstructured C-terminal domain of the CtBP transcriptional corepressor
The C-terminal Binding Protein (CtBP) is a transcriptional corepressor that plays critical roles in development, tumorigenesis, and cell fate. CtBP proteins are structurally similar to alpha hydroxyacid dehydrogenases and feature a prominent intrinsically disordered region in the C-terminus. In the...
Autores principales: | Raicu, Ana-Maria, Suresh, Megha, Arnosti, David N. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10245716/ https://www.ncbi.nlm.nih.gov/pubmed/37292674 http://dx.doi.org/10.1101/2023.05.19.541472 |
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