Central in vivo mechanisms by which C. difficile’s proline reductase drives efficient metabolism, growth, and toxin production

Clostridioides difficile (CD) is a sporulating and toxin-producing nosocomial pathogen that opportunistically infects the gut, particularly in patients with depleted microbiota after antibiotic exposure. Metabolically, CD rapidly generates energy and substrates for growth from Stickland fermentation...

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Detalles Bibliográficos
Autores principales: Cersosimo, Laura M., Graham, Madeline, Monestier, Auriane, Pavao, Aidan, Worley, Jay N., Peltier, Johann, Dupuy, Bruno, Bry, Lynn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10245720/
https://www.ncbi.nlm.nih.gov/pubmed/37292778
http://dx.doi.org/10.1101/2023.05.19.541423

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10245720/
https://www.ncbi.nlm.nih.gov/pubmed/37292778
http://dx.doi.org/10.1101/2023.05.19.541423

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