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Central in vivo mechanisms by which C. difficile’s proline reductase drives efficient metabolism, growth, and toxin production
Clostridioides difficile (CD) is a sporulating and toxin-producing nosocomial pathogen that opportunistically infects the gut, particularly in patients with depleted microbiota after antibiotic exposure. Metabolically, CD rapidly generates energy and substrates for growth from Stickland fermentation...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Cold Spring Harbor Laboratory
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10245720/ https://www.ncbi.nlm.nih.gov/pubmed/37292778 http://dx.doi.org/10.1101/2023.05.19.541423 |