Retinoblastoma protein activity revealed by CRISPRi study of divergent Rbf1 and Rbf2 paralogs

Retinoblastoma tumor suppressor proteins regulate the key transition from G1 to S phase of the cell cycle. The mammalian Rb family comprises Rb, p107, and p130, with overlapping and unique roles in gene regulation. Drosophila experienced an independent gene duplication event, leading to the Rbf1 and...

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Detalles Bibliográficos
Autores principales: Raicu, Ana-Maria, Castanheira, Patricia, Arnosti, David N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10245722/
https://www.ncbi.nlm.nih.gov/pubmed/37293052
http://dx.doi.org/10.1101/2023.05.19.541454

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10245722/
https://www.ncbi.nlm.nih.gov/pubmed/37293052
http://dx.doi.org/10.1101/2023.05.19.541454

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