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Retinoblastoma protein activity revealed by CRISPRi study of divergent Rbf1 and Rbf2 paralogs
Retinoblastoma tumor suppressor proteins regulate the key transition from G1 to S phase of the cell cycle. The mammalian Rb family comprises Rb, p107, and p130, with overlapping and unique roles in gene regulation. Drosophila experienced an independent gene duplication event, leading to the Rbf1 and...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Cold Spring Harbor Laboratory
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10245722/ https://www.ncbi.nlm.nih.gov/pubmed/37293052 http://dx.doi.org/10.1101/2023.05.19.541454 |