Cargando…

Scaling the Discrete-time Wright Fisher model to biobank-scale datasets

The Discrete-Time Wright Fisher (DTWF) model and its large population diffusion limit are central to population genetics. These models describe the forward-in-time evolution of the frequency of an allele in a population and can include the fundamental forces of genetic drift, mutation, and selection...

Descripción completa

Detalles Bibliográficos
Autores principales: Spence, Jeffrey P., Zeng, Tony, Mostafavi, Hakhamanesh, Pritchard, Jonathan K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10245735/
https://www.ncbi.nlm.nih.gov/pubmed/37293115
http://dx.doi.org/10.1101/2023.05.19.541517