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Scaling the Discrete-time Wright Fisher model to biobank-scale datasets
The Discrete-Time Wright Fisher (DTWF) model and its large population diffusion limit are central to population genetics. These models describe the forward-in-time evolution of the frequency of an allele in a population and can include the fundamental forces of genetic drift, mutation, and selection...
Autores principales: | Spence, Jeffrey P., Zeng, Tony, Mostafavi, Hakhamanesh, Pritchard, Jonathan K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10245735/ https://www.ncbi.nlm.nih.gov/pubmed/37293115 http://dx.doi.org/10.1101/2023.05.19.541517 |
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