Engineered bacteria titrate hydrogen sulfide and induce concentration-dependent effects on host in a gut microphysiological system

Hydrogen sulfide (H(2)S) is a gaseous microbial metabolite whose role in gut diseases is debated, largely due to the difficulty in controlling its concentration and the use of non-representative model systems in previous work. Here, we engineered E. coli to titrate H(2)S controllably across the phys...

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Detalles Bibliográficos
Autores principales: Hayes, Justin A., Lunger, Anna W., Sharma, Aayushi S., Fernez, Matthew T., Koppes, Abigail N., Koppes, Ryan, Woolston, Benjamin M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10245736/
https://www.ncbi.nlm.nih.gov/pubmed/37293009
http://dx.doi.org/10.1101/2023.05.16.538950

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10245736/
https://www.ncbi.nlm.nih.gov/pubmed/37293009
http://dx.doi.org/10.1101/2023.05.16.538950

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