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Engineered bacteria titrate hydrogen sulfide and induce concentration-dependent effects on host in a gut microphysiological system
Hydrogen sulfide (H(2)S) is a gaseous microbial metabolite whose role in gut diseases is debated, largely due to the difficulty in controlling its concentration and the use of non-representative model systems in previous work. Here, we engineered E. coli to titrate H(2)S controllably across the phys...
Autores principales: | Hayes, Justin A., Lunger, Anna W., Sharma, Aayushi S., Fernez, Matthew T., Koppes, Abigail N., Koppes, Ryan, Woolston, Benjamin M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10245736/ https://www.ncbi.nlm.nih.gov/pubmed/37293009 http://dx.doi.org/10.1101/2023.05.16.538950 |
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