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Disrupted memory T cell expansion in HIV-exposed uninfected infants is preceded by premature skewing of T cell receptor clonality

While preventing vertical HIV transmission has been very successful, the increasing number of HIV-exposed uninfected infants (iHEU) experience an elevated risk to infections compared to HIV-unexposed and uninfected infants (iHUU). Immune developmental differences between iHEU and iHUU remains poorly...

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Detalles Bibliográficos
Autores principales: Dzanibe, Sonwabile, Wilk, Aaron J., Canny, Susan, Ranganath, Thanmayi, Alinde, Berenice, Rubelt, Florian, Huang, Huang, Davis, Mark M., Holmes, Susan, Jaspan, Heather B., Blish, Catherine A., Gray, Clive M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10245741/
https://www.ncbi.nlm.nih.gov/pubmed/37292866
http://dx.doi.org/10.1101/2023.05.19.540713