Regulation of RNA methylation by therapy treatment, promotes tumor survival

Our data previously revealed that chemosurviving cancer cells translate specific genes. Here, we find that the m6A-RNA-methyltransferase, METTL3, increases transiently in chemotherapy-treated breast cancer and leukemic cells in vitro and in vivo. Consistently, m6A increases on RNA from chemo-treated...

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Detalles Bibliográficos
Autores principales: Bukhari, Syed IA, Truesdell, Samuel S, Datta, Chandreyee, Choudhury, Pritha, Wu, Keith Q, Shrestha, Jitendra, Maharjan, Ruby, Plotsker, Ethan, Elased, Ramzi, Laisa, Sadia, Bhambhani, Vijeta, Lin, Yue, Kreuzer, Johannes, Morris, Robert, Koh, Siang-Boon, Ellisen, Leif W., Haas, Wilhelm, Ly, Amy, Vasudevan, Shobha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10245743/
https://www.ncbi.nlm.nih.gov/pubmed/37292633
http://dx.doi.org/10.1101/2023.05.19.540602

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10245743/
https://www.ncbi.nlm.nih.gov/pubmed/37292633
http://dx.doi.org/10.1101/2023.05.19.540602

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