Structure and dynamics of cholesterol-mediated aquaporin-0 arrays and implications for lipid rafts

Aquaporin-0 (AQP0) tetramers form square arrays in lens membranes through a yet unknown mechanism, but lens membranes are enriched in sphingomyelin and cholesterol. Here, we determined electron crystallographic structures of AQP0 in sphingomyelin/ cholesterol membranes and performed molecular dynami...

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Detalles Bibliográficos
Autores principales: Chiu, Po-Lin, Orjuela, Juan D., de Groot, Bert L., Aponte-Santamaría, Camilo, Walz, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10245776/
https://www.ncbi.nlm.nih.gov/pubmed/37292626
http://dx.doi.org/10.1101/2023.05.16.540959

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10245776/
https://www.ncbi.nlm.nih.gov/pubmed/37292626
http://dx.doi.org/10.1101/2023.05.16.540959

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