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Predicting structures of large protein assemblies using combinatorial assembly algorithm and AlphaFold2
Deep learning models, such as AlphaFold2 and RosettaFold, enable high-accuracy protein structure prediction. However, large protein complexes are still challenging to predict due to their size and the complexity of interactions between multiple subunits. Here we present CombFold, a combinatorial and...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10245790/ https://www.ncbi.nlm.nih.gov/pubmed/37293053 http://dx.doi.org/10.1101/2023.05.16.541003 |