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PfAP2-MRP DNA-binding protein is a master regulator of parasite pathogenesis during malaria parasite blood stages

Malaria pathogenicity results from the parasite’s ability to invade, multiply within and then egress from the host red blood cell (RBC). Infected RBCs are remodeled, expressing antigenic variant proteins (such as PfEMP1, coded by the var gene family) for immune evasion and survival. These processes...

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Detalles Bibliográficos
Autores principales: Subudhi, Amit Kumar, Green, Judith L., Satyam, Rohit, Lenz, Todd, Salunke, Rahul P., Shuaib, Muhammad, Isaioglou, Ioannis, Abel, Steven, Gupta, Mohit, Esau, Luke, Mourier, Tobias, Nugmanova, Raushan, Mfarrej, Sara, Sivapurkar, Rupali, Stead, Zenaida, Rached, Fathia Ben, Otswal, Yogesh, Sougrat, Rachid, Dada, Ashraf, Kadamany, Abdullah Fuaad, Fischle, Wolfgang, Merzaban, Jasmeen, Knuepfer, Ellen, Ferguson, David J.P., Gupta, Ishaan, Le Roch, Karine G., Holder, Anthony A., Pain, Arnab
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10245809/
https://www.ncbi.nlm.nih.gov/pubmed/37293082
http://dx.doi.org/10.1101/2023.05.23.541898