PKCδ regulates chromatin remodeling and DNA repair through SIRT6

Protein kinase C delta (PKCδ) is a ubiquitous kinase whose function is defined in part by localization to specific cellular compartments. Nuclear PKCδ is both necessary and sufficient for IR-induced apoptosis, while inhibition of PKCδ activity provides radioprotection in vivo. How nuclear PKCδ regul...

Descripción completa

Detalles Bibliográficos
Autores principales: Affandi, Trisiani, Haas, Ami, Ohm, Angela M., Wright, Gregory M., Black, Joshua C., Reyland, Mary E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10245827/
https://www.ncbi.nlm.nih.gov/pubmed/37292592
http://dx.doi.org/10.1101/2023.05.24.541991

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10245827/
https://www.ncbi.nlm.nih.gov/pubmed/37292592
http://dx.doi.org/10.1101/2023.05.24.541991

Ejemplares similares