Sex and gonadectomy modify behavioral seizure susceptibility and mortality in a repeated low-dose kainic acid systemic injection paradigm in mice

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OBJECTIVE: Sex differences in epilepsy appear driven in part due to effects of gonadal steroids, with varying results in experimental models based on species, strain, and method of seizure induction. Furthermore, removing a main source of these steroids via gonadectomy may impact seizure characteris...

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Detalles Bibliográficos
Autores principales: Lawande, Niraj V., Conklin, Elisabeth A., Christian-Hinman, Catherine A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10245840/
https://www.ncbi.nlm.nih.gov/pubmed/37292790
http://dx.doi.org/10.1101/2023.05.22.541824

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10245840/
https://www.ncbi.nlm.nih.gov/pubmed/37292790
http://dx.doi.org/10.1101/2023.05.22.541824

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