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Inferring chromosomal instability from copy number aberrations as a measure of chromosomal instability across human cancers

BACKGROUND: Cancer is a complex disease that is the second leading cause of death in the United States. Despite research efforts, the ability to manage cancer and select optimal therapeutic responses for each patient remains elusive. Chromosomal instability (CIN) is primarily a product of segregatio...

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Detalles Bibliográficos
Autores principales: Taluri, Sasha, Oza, Vishal H., Soelter, Tabea M., Fisher, Jennifer L., Lasseigne, Brittany N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10245901/
https://www.ncbi.nlm.nih.gov/pubmed/37292608
http://dx.doi.org/10.1101/2023.05.24.542174