Microbiota produced indole metabolites disrupt host cell mitochondrial energy production and inhibit Cryptosporidium parvum growth

Cryptosporidiosis is a leading cause of life-threatening diarrhea in young children in resource-poor settings. Susceptibility rapidly declines with age, associated with changes in the microbiota. To explore microbial influences on susceptibility, we screened 85 microbiota-associated metabolites enri...

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Detalles Bibliográficos
Autores principales: Funkhouser-Jones, Lisa J., Xu, Rui, Wilke, Georgia, Fu, Yong, Shriefer, Lawrence A., Makimaa, Heyde, Rodgers, Rachel, Kennedy, Elizabeth A., VanDussen, Kelli L., Stappenbeck, Thaddeus S., Baldridge, Megan T., Sibley, L. David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10245909/
https://www.ncbi.nlm.nih.gov/pubmed/37292732
http://dx.doi.org/10.1101/2023.05.25.542157

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10245909/
https://www.ncbi.nlm.nih.gov/pubmed/37292732
http://dx.doi.org/10.1101/2023.05.25.542157

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