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Sessile alveolar macrophage connexin-43 determines mechano-immunity in the lung

Although lung immunity is pathogen induced, the immunity can also be induced by mechanical distortion of the lung. The causal basis of the lung’s mechanosensitive immunity remains unclear. Here, through live optical imaging of mouse lungs, we show that alveolar stretch due to hyperinflation induced...

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Detalles Bibliográficos
Autores principales: Mthunzi, Liberty, Gusarova, Galina A, Islam, Mohammad N, Bhattacharya, Sunita, Bhattacharya, Jahar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10245918/
https://www.ncbi.nlm.nih.gov/pubmed/37292826
http://dx.doi.org/10.1101/2023.05.24.541735