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Growth factor-free, peptide-functionalized gelatin hydrogel promotes arteriogenesis and attenuates tissue damage in a murine model of critical limb ischemia

Critical limb ischemia (CLI) occurs when blood flow is restricted through the arteries, resulting in ulcers, necrosis, and chronic wounds in the downstream extremities. The development of collateral arterioles (i.e. arteriogenesis), either by remodeling of pre-existing vascular networks or de novo g...

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Detalles Bibliográficos
Autores principales: Curry, Corinne W., Sturgeon, Sarah M., O’Grady, Brian J., Yates, Alexis K., Kjar, Andrew, Paige, Hayden A., Mowery, Lucas S., Katdare, Ketaki A., Patel, Riya V., Mlouk, Kate, Stiefbold, Madison R., Vafaie-Partin, Sidney, Kawabata, Atsuyuki, McKee, Rachel M., Moore-Lotridge, Stephanie, Hawkes, Adrienne, Kusunose, Jiro, Gibson-Corley, Katherine N., Schmeckpeper, Jeffrey, Schoenecker, Jonathan G., Caskey, Charles F., Lippmann, Ethan S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10245920/
https://www.ncbi.nlm.nih.gov/pubmed/37292898
http://dx.doi.org/10.1101/2023.05.24.542150