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Alterations in the preneoplastic breast microenvironment of BRCA1/2 mutation carriers revealed by spatial transcriptomics

Breast cancer is the most common cancer in females, affecting one in every eight women and accounting for the majority of cancer-related deaths in women worldwide. Germline mutations in the BRCA1 and BRCA2 genes are significant risk factors for specific subtypes of breast cancer. BRCA1 mutations are...

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Detalles Bibliográficos
Autores principales: Caputo, Anthony, Vipparthi, Kavya, Bazeley, Peter, Downs-Kelly, Erinn, McIntire, Patrick, Ni, Ying, Hu, Bo, Keri, Ruth A., Karaayvaz, Mihriban
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10245938/
https://www.ncbi.nlm.nih.gov/pubmed/37292816
http://dx.doi.org/10.1101/2023.05.24.542078