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Cell type deconvolution of bulk blood RNA-Seq to reveal biological insights of neuropsychiatric disorders

Genome-wide association studies (GWAS) have uncovered susceptibility loci associated with psychiatric disorders like bipolar disorder (BP) and schizophrenia (SCZ). However, most of these loci are in non-coding regions of the genome with unknown causal mechanisms of the link between genetic variation...

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Detalles Bibliográficos
Autores principales: Boltz, Toni, Schwarz, Tommer, Bot, Merel, Hou, Kangcheng, Caggiano, Christa, Lapinska, Sandra, Duan, Chenda, Boks, Marco P., Kahn, Rene S., Zaitlen, Noah, Pasaniuc, Bogdan, Ophoff, Roel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10245943/
https://www.ncbi.nlm.nih.gov/pubmed/37293101
http://dx.doi.org/10.1101/2023.05.24.542156