Transcription start site heterogeneity and its role in RNA fate determination distinguish HIV-1 from other retroviruses and are mediated by core promoter elements

HIV-1 uses heterogeneous transcription start sites (TSSs) to generate two RNA 5’ isoforms that adopt radically different structures and perform distinct replication functions. Although these RNAs differ in length by only two bases, exclusively the shorter RNA is encapsidated while the longer RNA is...

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Detalles Bibliográficos
Autores principales: Kharytonchyk, Siarhei, Burnett, Cleo, GC, Keshav, Telesnitsky, Alice
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10245945/
https://www.ncbi.nlm.nih.gov/pubmed/37292892
http://dx.doi.org/10.1101/2023.05.22.541776

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10245945/
https://www.ncbi.nlm.nih.gov/pubmed/37292892
http://dx.doi.org/10.1101/2023.05.22.541776

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