Single-cell transcriptomic analysis of skeletal muscle regeneration across mouse lifespan identifies altered stem cell states associated with senescence

Skeletal muscle regeneration is driven by the interaction of myogenic and non-myogenic cells. In aging, regeneration is impaired due to dysfunctions of myogenic and non-myogenic cells, but this is not understood comprehensively. We collected an integrated atlas of 273,923 single-cell transcriptomes...

Descripción completa

Detalles Bibliográficos
Autores principales: Walter, Lauren D., Orton, Jessica L., Hannah Fong, Ern Hwei, Maymi, Viviana I., Rudd, Brian D., Elisseeff, Jennifer H., Cosgrove, Benjamin D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10245980/
https://www.ncbi.nlm.nih.gov/pubmed/37292698
http://dx.doi.org/10.1101/2023.05.25.542370

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10245980/
https://www.ncbi.nlm.nih.gov/pubmed/37292698
http://dx.doi.org/10.1101/2023.05.25.542370

Ejemplares similares