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Single-cell transcriptomic analysis of skeletal muscle regeneration across mouse lifespan identifies altered stem cell states associated with senescence
Skeletal muscle regeneration is driven by the interaction of myogenic and non-myogenic cells. In aging, regeneration is impaired due to dysfunctions of myogenic and non-myogenic cells, but this is not understood comprehensively. We collected an integrated atlas of 273,923 single-cell transcriptomes...
Autores principales: | Walter, Lauren D., Orton, Jessica L., Hannah Fong, Ern Hwei, Maymi, Viviana I., Rudd, Brian D., Elisseeff, Jennifer H., Cosgrove, Benjamin D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10245980/ https://www.ncbi.nlm.nih.gov/pubmed/37292698 http://dx.doi.org/10.1101/2023.05.25.542370 |
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