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An evolutionary mechanism to assimilate new nutrient sensors into the mTORC1 pathway

Animals must sense and respond to nutrient availability in their local niche. This task is coordinated in part by the mTOR complex 1 (mTORC1) pathway, which regulates growth and metabolism in response to nutrients(1–5). In mammals, mTORC1 senses specific amino acids through specialized sensors that...

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Detalles Bibliográficos
Autores principales: Liu, Grace Y., Jouandin, Patrick, Bahng, Raymond E., Perrimon, Norbert, Sabatini, David M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10245982/
https://www.ncbi.nlm.nih.gov/pubmed/37292894
http://dx.doi.org/10.1101/2023.05.25.541239