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Pien-Tze-Huang prevents hepatocellular carcinoma by inducing ferroptosis via inhibiting SLC7A11-GSH-GPX4 axis

BACKGROUND: Malignant transformation from hepatic fibrosis to carcinogenesis may be a therapeutic target for hepatocellular carcinoma (HCC). The aim of this study was to evaluate anti-cancer efficacy of Pien-Tze-Huang (PZH), and to investigate the underlying mechanisms by integrating transcriptional...

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Detalles Bibliográficos
Autores principales: Yan, Xiangying, Liu, Yudong, Li, Congchong, Mao, Xia, Xu, Tengteng, Hu, Zhixing, Zhang, Chu, Lin, Na, Lin, Ya, Zhang, Yanqiong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10246043/
https://www.ncbi.nlm.nih.gov/pubmed/37280673
http://dx.doi.org/10.1186/s12935-023-02946-2