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Spatial genomic, biochemical, and cellular mechanisms drive meningioma heterogeneity and evolution

Intratumor heterogeneity underlies cancer evolution and treatment resistance(1–5), but targetable mechanisms driving intratumor heterogeneity are poorly understood. Meningiomas are the most common primary intracranial tumors and are resistant to all current medical therapies(6,7). High-grade meningi...

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Detalles Bibliográficos
Autores principales: Lucas, Calixto-Hope, Mirchia, Kanish, Seo, Kyounghee, Najem, Hinda, Chen, William, Zakimi, Naomi, Choudhury, Abrar, Liu, S. John, Phillips, Joanna, Magill, Stephen, Horbinski, Craig, Solomon, David, Perry, Arie, Vasudevan, Harish, Heimberger, Amy, Raleigh, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10246120/
https://www.ncbi.nlm.nih.gov/pubmed/37292686
http://dx.doi.org/10.21203/rs.3.rs-2921804/v1