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Spatial genomic, biochemical, and cellular mechanisms drive meningioma heterogeneity and evolution
Intratumor heterogeneity underlies cancer evolution and treatment resistance(1–5), but targetable mechanisms driving intratumor heterogeneity are poorly understood. Meningiomas are the most common primary intracranial tumors and are resistant to all current medical therapies(6,7). High-grade meningi...
Autores principales: | Lucas, Calixto-Hope, Mirchia, Kanish, Seo, Kyounghee, Najem, Hinda, Chen, William, Zakimi, Naomi, Choudhury, Abrar, Liu, S. John, Phillips, Joanna, Magill, Stephen, Horbinski, Craig, Solomon, David, Perry, Arie, Vasudevan, Harish, Heimberger, Amy, Raleigh, David |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Journal Experts
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10246120/ https://www.ncbi.nlm.nih.gov/pubmed/37292686 http://dx.doi.org/10.21203/rs.3.rs-2921804/v1 |
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