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Distinct T cell functional profiles in SARS-CoV-2 seropositive and seronegative children associated with endemic human coronavirus cross-reactivity

SARS-CoV-2 infection in children typically results in asymptomatic or mild disease. There is a paucity of studies on antiviral immunity in African children. We investigated SARS-CoV-2-specific T cell responses in 71 unvaccinated asymptomatic South African children who were seropositive or seronegati...

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Detalles Bibliográficos
Autores principales: Benede, Ntombi S. B., Tincho, Marius B., Walters, Avril, Subbiah, Vennesa, Ngomti, Amkele, Baguma, Richard, Butters, Claire, Mennen, Mathilda, Skelem, Sango, Adriaanse, Marguerite, van Graan, Strauss, Balla, Sashkia R., Moyo-Gwete, Thandeka, Moore, Penny L., Botha, Maresa, Workman, Lesley, Zar, Heather J., Ntusi, Ntobeko A. B., Zühlke, Liesl, Webb, Kate, Riou, Catherine, Burgers, Wendy A., Keeton, Roanne S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10246143/
https://www.ncbi.nlm.nih.gov/pubmed/37292954
http://dx.doi.org/10.1101/2023.05.16.23290059