Genome-wide association study stratified by MAPT haplotypes identifies potential novel loci in Parkinson’s disease

OBJECTIVE: To identify genetic factors that may modify the effects of the MAPT locus in Parkinson’s disease (PD). METHODS: We used data from the International Parkinson’s Disease Genomics Consortium (IPDGC) and the UK biobank (UKBB). We stratified the IPDGC cohort for carriers of the H1/H1 genotype...

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Detalles Bibliográficos
Autores principales: Senkevich, Konstantin, Bandres-Ciga, Sara, Cisterna-García, Alejandro, Yu, Eric, Bustos, Bernabe I., Krohn, Lynne, Lubbe, Steven J., Botía, Juan A., Gan-Or, Ziv
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10246147/
https://www.ncbi.nlm.nih.gov/pubmed/37292720
http://dx.doi.org/10.1101/2023.04.14.23288478

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10246147/
https://www.ncbi.nlm.nih.gov/pubmed/37292720
http://dx.doi.org/10.1101/2023.04.14.23288478

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