Single-cell sequencing dissects the transcriptional identity of activated fibroblasts and identifies novel persistent distal tubular injury patterns in kidney fibrosis

Examining kidney fibrosis is crucial for mechanistic understanding and developing targeted strategies against chronic kidney disease (CKD). Persistent fibroblast activation and tubular epithelial cell (TEC) injury are key CKD contributors. However, cellular and transcriptional landscapes of CKD and...

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Detalles Bibliográficos
Autores principales: Rudman-Melnick, Valeria, Adam, Mike, Stowers, Kaitlynn, Potter, Andrew, Ma, Qing, Chokshi, Saagar M., Vanhoutte, Davy, Valiente-Alandi, Iñigo, Lindquist, Diana M., Nieman, Michelle L., Kofron, J. Matthew, Potter, S. Steven, Devarajan, Prasad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10246229/
https://www.ncbi.nlm.nih.gov/pubmed/37293022
http://dx.doi.org/10.21203/rs.3.rs-2880248/v1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10246229/
https://www.ncbi.nlm.nih.gov/pubmed/37293022
http://dx.doi.org/10.21203/rs.3.rs-2880248/v1

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