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VprBP/DCAF1 triggers melanomagenic gene silencing through histone H2A phosphorylation
BACKGROUND: Melanoma is the most aggressive form of skin cancer arising from pigment-producing melanocytes and is often associated with dysregulation of epigenetic factors targeting histones. VprBP, also known as DCAF1, is a recently identified kinase and plays an important role in downregulating th...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Journal Experts
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10246234/ https://www.ncbi.nlm.nih.gov/pubmed/37293029 http://dx.doi.org/10.21203/rs.3.rs-2950076/v2 |