VprBP/DCAF1 triggers melanomagenic gene silencing through histone H2A phosphorylation

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BACKGROUND: Melanoma is the most aggressive form of skin cancer arising from pigment-producing melanocytes and is often associated with dysregulation of epigenetic factors targeting histones. VprBP, also known as DCAF1, is a recently identified kinase and plays an important role in downregulating th...

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Detalles Bibliográficos
Autores principales: Shin, Yonghwan, Kim, Sungmin, Liang, Gangning, Ulmer, Tobias S, An, Woojin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10246234/
https://www.ncbi.nlm.nih.gov/pubmed/37293029
http://dx.doi.org/10.21203/rs.3.rs-2950076/v2

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